Genetic variations and haplotypes of CYP2C19 in a Japanese population.

H, Fukushima-Uesaka; Y, Saito; K, Maekawa; S, Ozawa; R, Hasegawa; H, Kajio; N, Kuzuya; K, Yasuda; M, Kawamoto; N, Kamatani; K, Suzuki; T, Yanagawa; M, Tohkin; J, Sawada

doi:10.2133/dmpk.20.300

Public

Genetic variations and haplotypes of CYP2C19 in a Japanese population.

Shared by NobleBlocks on Aug 1, 2005 • 12:00 AM UTC

Authors:

Fukushima-Uesaka H

Saito Y

Maekawa K

Abstract

Forty-eight single nucleotide variations, including 27 novel ones, were found in the 5'- regulatory region, all of the exons and their surrounding introns of CYP2C19 in 253 Japanese subjects (134 diabetic patients and 119 healthy volunteers). Identified novel variations were as follows: -2772G>A, 27...

Discussions