Taxol and Taxane Production by
            <i>Taxomyces andreanae</i>
            , an Endophytic Fungus of Pacific Yew

Stierle, Andrea; Strobel, Gary; Stierle, Donald

doi:10.1126/science.8097061

Public

Taxol and Taxane Production by <i>Taxomyces andreanae</i> , an Endophytic Fungus of Pacific Yew

Shared by NobleBlocks on Apr 9, 1993 • 12:00 AM UTC

Authors:

Andrea Stierle

Gary Strobel

Donald Stierle

Abstract

Taxomyces andreanae , a fungal endophyte, was isolated from the phloem (inner bark) of the Pacific yew, Taxus brevifolia . The fungus is hyphomyceteous and, when grown in a semi-synthetic liquid medium, produced taxol and related compounds. Taxol was identified by mass spectrometry, chromatography, ...

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