Impaired Neural Response to Negative Prediction Errors in Cocaine Addiction

A. Parvaz, Muhammad; B. Konova, Anna; Hajcak, Greg; P. Dunning, Jonathan; Malaker, Pias; J. Moeller, Scott; Maloney, Tom; Alia‐Klein, Nelly; Z. Goldstein, Rita

doi:10.1523/jneurosci.2777-14.2015

Public

Impaired Neural Response to Negative Prediction Errors in Cocaine Addiction

Published in Journal of Neuroscience • Feb 4, 2015

Authors:

Muhammad A. Parvaz

Anna B. Konova

Greg Hajcak

Abstract

Learning can be guided by unexpected success or failure, signaled via dopaminergic positive reward prediction error (+RPE) and negative reward-prediction error (-RPE) signals, respectively. Despite conflicting empirical evidence, RPE signaling is thought to be impaired in drug addiction. To resolve ...

View

Open Access

Subject

Addiction

Psychology

Dopaminergic

Generate AI Take for this paper

Highlights, strengths & weaknesses, commercial applications, and societal impact — written for this paper on demand.

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!