Molecular cloning, expression and chromosomal localisation of human AMP-activated protein kinase.

RK, Beri; AE, Marley; CG, See; WF, Sopwith; K, Aguan; D, Carling; J, Scott; F, Carey

doi:10.1016/0014-5793(94)01247-4

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Molecular cloning, expression and chromosomal localisation of human AMP-activated protein kinase.

Shared by NobleBlocks on Dec 1, 1994 • 12:00 AM UTC

Authors:

Beri RK

Marley AE

See CG

Abstract

A cDNA encoding rat liver AMP-activated protein kinase (AMPK) was used to isolate human skeletal muscle AMPK cDNA clones. Human AMPK cDNA is more than 90% homologous to the rat sequence and predicts a protein of molecular mass 62.3 kDa, which closely agrees with the mass observed in Western blots of...

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