Multiple sclerosis: capping of surface immunoglobulin G on macrophages engaged in myelin breakdown.

Macrophages were examined for immunoglobulin G (IgG) and albumin in actively demyelinating lesions in two patients with multiple sclerosis (MS) using the peroxidase-antiperoxidase immunocytochemical technique. In both cases, macrophages were present that stained for cytoplasmic or surface IgG or bot... View More