Antiviral responses in mouse embryonic stem cells: differential development of cellular mechanisms in type I interferon production and response.

R, Wang; J, Wang; D, Acharya; AM, Paul; F, Bai; F, Huang; YL, Guo

doi:10.1074/jbc.m113.537746

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Antiviral responses in mouse embryonic stem cells: differential development of cellular mechanisms in type I interferon production and response.

Shared by NobleBlocks on Jun 25, 2014 • 12:00 AM UTC

Authors:

Wang R

Wang J

Acharya D

Abstract

We have recently reported that mouse embryonic stem cells (mESCs) are deficient in expressing type I interferons (IFNs) in response to viral infection and synthetic viral RNA analogs (Wang, R., Wang, J., Paul, A. M., Acharya, D., Bai, F., Huang, F., and Guo, Y. L. (2013) J. Biol. Chem. 288, 15926-15...

Subject

Interferon

Embryonic stem cell

viral replication

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