Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes.

V Castell, J; J Gómez-Lechón, M; David, M; Hirano, T; Kishimoto, T; C Heinrich, P

doi:10.1016/0014-5793(88)80766-x

Public

Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes.

Shared by NobleBlocks on May 23, 1988 • 12:00 AM UTC

Authors:

J V Castell

M J Gómez-Lechón

M David

Abstract

Recombinant human IL-6 (rhIL-6) is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes. A wide spectrum of acute phase proteins is regulated by this mediator. After labeling of rhIL-6 stimulated human hepatocytes with [35S]methionine acute phase protein synthesis was...

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