Novel liver macromolecular MR contrast agent with a polypropylenimine diaminobutyl dendrimer core: comparison to the vascular MR contrast agent with the polyamidoamine dendrimer core.

H, Kobayashi; S, Kawamoto; T, Saga; N, Sato; A, Hiraga; T, Ishimori; Y, Akita; MH, Mamede; J, Konishi; K, Togashi; MW, Brechbiel

doi:10.1002/mrm.1259

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Novel liver macromolecular MR contrast agent with a polypropylenimine diaminobutyl dendrimer core: comparison to the vascular MR contrast agent with the polyamidoamine dendrimer core.

Shared by NobleBlocks on Oct 1, 2001 • 12:00 AM UTC

Authors:

Kobayashi H

Kawamoto S

Saga T

Abstract

As MRI contrast agents, more hydrophobic molecules reportedly accumulate in the liver and thus are potentially useful as liver MRI contrast agents. In this study, a generation-4 polypropylenimine diaminobutane dendrimer (DAB-Am64), which is expected to be more hydrophobic than the generation-4 polya...

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