MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma.

WC, Tsai; PW, Hsu; TC, Lai; GY, Chau; CW, Lin; CM, Chen; CD, Lin; YL, Liao; JL, Wang; YP, Chau; MT, Hsu; M, Hsiao; HD, Huang; AP, Tsou

doi:10.1002/hep.22806

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MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma.

Shared by NobleBlocks on May 1, 2009 • 12:00 AM UTC

Authors:

Tsai WC

Hsu PW

Lai TC

Abstract

<h4>Unlabelled</h4>MicroRNAs (miRNAs), which are inhibitors of gene expression, participate in diverse biological functions and in carcinogenesis. In this study, we show that liver-specific microRNA-122 (miR-122) is significantly down-regulated in liver cancers with intrahepatic metastasis and negat...

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