A Trial of Shortened Zidovudine Regimens to Prevent Mother-to-Child Transmission of Human Immunodeficiency Virus Type 1

Lallemant, Marc; Jourdain, Gonzague; Le Coeur, Sophie; Kim, Soyeon; Koetsawang, Suporn; Marie Comeau, Anne; Phoolcharoen, Wiput; Essex, Max; McIntosh, Kenneth; Vithayasai, Vicharn

doi:10.1056/nejm200010053431401

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A Trial of Shortened Zidovudine Regimens to Prevent Mother-to-Child Transmission of Human Immunodeficiency Virus Type 1

Published in New England Journal of Medicine • Oct 5, 2000

Authors:

Marc Lallemant

Gonzague Jourdain

Sophie Le Coeur

Abstract

BACKGROUND: The optimal duration of zidovudine administration to prevent perinatal transmission of human immunodeficiency virus type 1 (HIV-1) should be determined to facilitate its use in areas where resources are limited. METHODS: We conducted a randomized, double-blind equivalence trial of zidovu...

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Open Access

Subject

Regimen

Zidovudine

Medicine

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