High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.

M, Logozzi; Milito A, De; L, Lugini; M, Borghi; L, Calabrò; M, Spada; M, Perdicchio; ML, Marino; C, Federici; E, Iessi; D, Brambilla; G, Venturi; F, Lozupone; M, Santinami; V, Huber; M, Maio; L, Rivoltini; S, Fais

doi:10.1371/journal.pone.0005219

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High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.

Shared by NobleBlocks on Apr 17, 2009 • 12:00 AM UTC

Authors:

Logozzi M

De Milito A

Lugini L

Abstract

<h4>Background</h4>Metastatic melanoma is an untreatable cancer lacking reliable and non-invasive markers of disease progression. Exosomes are small vesicles secreted by normal as well as tumor cells. Human tumor-derived exosomes are involved in malignant progression and we evaluated the presence of...

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