Stress protein-induced immunosuppression: inhibition of cellular immune effector functions following overexpression of haem oxygenase (HSP 32).

J, Woo; S, Iyer; MC, Cornejo; N, Mori; L, Gao; I, Sipos; M, Maines; R, Buelow

doi:10.1016/s0966-3274(98)80022-1

Public

Stress protein-induced immunosuppression: inhibition of cellular immune effector functions following overexpression of haem oxygenase (HSP 32).

Shared by NobleBlocks on Jun 1, 1998 • 12:00 AM UTC

Authors:

Woo J

Iyer S

Cornejo MC

Abstract

This is the first report on suppression of immune effector functions following upregulation of heat shock protein 32 (HSP 32), known as haem oxygenase (HO-1). Here we evaluated the effect of cobalt-protoporphyrin (CoPP)-induced HO-1 expression on cell-mediated immune responses. Administration of CoP...

Discussions