Right ventricular hypertrophy secondary to pulmonary hypertension is linked to rat chromosome 17: evaluation of cardiac ryanodine Ryr2 receptor as a candidate.

L, Zhao; A, Sebkhi; DJ, Nunez; L, Long; CS, Haley; J, Szpirer; C, Szpirer; AJ, Williams; MR, Wilkins

doi:10.1161/01.cir.103.3.442

Public

Right ventricular hypertrophy secondary to pulmonary hypertension is linked to rat chromosome 17: evaluation of cardiac ryanodine Ryr2 receptor as a candidate.

Shared by NobleBlocks on Jan 1, 2001 • 12:00 AM UTC

Authors:

Zhao L

Sebkhi A

Nunez DJ

Abstract

<h4>Background</h4>Fischer 344 (F344) rats are relatively resistant to hypoxia-induced right ventricular (RV) hypertrophy compared with the Wistar-Kyoto (WKY) strain. These 2 strains were used to examine the genetic basis for the differential response.<h4>Methods and results</h4>Male F(2) offspring ...

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