Tracking human migrations by the analysis of the distribution of HLA alleles, lineages and haplotypes in closed and open populations.

Vina MA, Fernandez; JA, Hollenbach; KE, Lyke; MB, Sztein; M, Maiers; W, Klitz; P, Cano; S, Mack; R, Single; C, Brautbar; S, Israel; E, Raimondi; E, Khoriaty; A, Inati; M, Andreani; M, Testi; ME, Moraes; G, Thomson; P, Stastny; K, Cao

doi:10.1098/rstb.2011.0320

Public

Tracking human migrations by the analysis of the distribution of HLA alleles, lineages and haplotypes in closed and open populations.

Shared by NobleBlocks on Mar 1, 2012 • 12:00 AM UTC

Authors:

Fernandez Vina MA

Hollenbach JA

Lyke KE

Abstract

The human leucocyte antigen (HLA) system shows extensive variation in the number and function of loci and the number of alleles present at any one locus. Allele distribution has been analysed in many populations through the course of several decades, and the implementation of molecular typing has si...

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