Detection of aneuploidy and chromosomal mosaicism in human embryos during preimplantation sex determination by fluorescent in situ hybridisation, (FISH).

JD, Delhanty; DK, Griffin; AH, Handyside; J, Harper; GH, Atkinson; MH, Pieters; RM, Winston

doi:10.1093/hmg/2.8.1183

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Detection of aneuploidy and chromosomal mosaicism in human embryos during preimplantation sex determination by fluorescent in situ hybridisation, (FISH).

Shared by NobleBlocks on Aug 1, 1993 • 12:00 AM UTC

Authors:

Delhanty JD

Griffin DK

Handyside AH

Abstract

Five couples at risk of producing offspring with X-linked recessive disease underwent in vitro fertilisation with a view to preimplantation determination of embryo sex and selective transfer of females. On day three postinsemination, one or two blastomeres were removed by embryo biopsy, and used for...

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