A low interleukin-10 tumor necrosis factor-alpha ratio is associated with malaria anemia in children residing in a holoendemic malaria region in western Kenya.

C, Othoro; AA, Lal; B, Nahlen; D, Koech; AS, Orago; V, Udhayakumar

doi:10.1086/314548

Public

A low interleukin-10 tumor necrosis factor-alpha ratio is associated with malaria anemia in children residing in a holoendemic malaria region in western Kenya.

Shared by NobleBlocks on Jan 1, 1999 • 12:00 AM UTC

Authors:

Othoro C

Lal AA

Nahlen B

Abstract

The balance between Th1 cytokines (tumor necrosis factor [TNF]-alpha, interferon [IFN]-gamma) and Th2 cytokines (interleukin [IL]-10, -4) may be critical in the development of severe falciparum malaria. Therefore, plasma concentrations of these cytokines were determined in children with various mani...

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