The effect of tofacitinib on pneumococcal and influenza vaccine responses in rheumatoid arthritis.

KL, Winthrop; J, Silverfield; A, Racewicz; J, Neal; EB, Lee; P, Hrycaj; J, Gomez-Reino; K, Soma; C, Mebus; B, Wilkinson; J, Hodge; H, Fan; T, Wang; CO 3rd, Bingham

doi:10.1136/annrheumdis-2014-207191

Public

The effect of tofacitinib on pneumococcal and influenza vaccine responses in rheumatoid arthritis.

Shared by NobleBlocks on Mar 20, 2015 • 12:00 AM UTC

Authors:

Winthrop KL

Silverfield J

Racewicz A

Abstract

<h4>Objective</h4>To evaluate tofacitinib's effect upon pneumococcal and influenza vaccine immunogenicity.<h4>Methods</h4>We conducted two studies in patients with rheumatoid arthritis using the 23-valent pneumococcal polysaccharide vaccine (PPSV-23) and the 2011-2012 trivalent influenza vaccine. In...

Subject

Rheumatoid arthritis

Vaccination

Infections

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