Cytogenetic prognostication within medulloblastoma subgroups.

DJ, Shih; PA, Northcott; M, Remke; A, Korshunov; V, Ramaswamy; M, Kool; B, Luu; Y, Yao; X, Wang; AM, Dubuc; L, Garzia; J, Peacock; SC, Mack; X, Wu; A, Rolider; AS, Morrissy; FM, Cavalli; DT, Jones; K, Zitterbart; CC, Faria; U, Schüller; L, Kren; T, Kumabe; T, Tominaga; Ra Y, Shin; M, Garami; P, Hauser; JA, Chan; S, Robinson; L, Bognár; A, Klekner; AG, Saad; LM, Liau; S, Albrecht; A, Fontebasso; G, Cinalli; Antonellis P, De; M, Zollo; MK, Cooper; RC, Thompson; S, Bailey; JC, Lindsey; Rocco C, Di; L, Massimi; EM, Michiels; SW, Scherer; JJ, Phillips; N, Gupta; X, Fan; KM, Muraszko; R, Vibhakar; CG, Eberhart; M, Fouladi; B, Lach; S, Jung; RJ, Wechsler-Reya; M, Fèvre-Montange; A, Jouvet; N, Jabado; IF, Pollack; WA, Weiss; JY, Lee; BK, Cho; SK, Kim; KC, Wang; JR, Leonard; JB, Rubin; Torres C, de; C, Lavarino; J, Mora; YJ, Cho; U, Tabori; JM, Olson; A, Gajjar; RJ, Packer; S, Rutkowski; SL, Pomeroy; PJ, French; NK, Kloosterhof; JM, Kros; Meir EG, Van; SC, Clifford; F, Bourdeaut; O, Delattre; FF, Doz; CE, Hawkins; D, Malkin; WA, Grajkowska; M, Perek-Polnik; E, Bouffet; JT, Rutka; SM, Pfister; MD, Taylor

doi:10.1200/jco.2013.50.9539

Public

Cytogenetic prognostication within medulloblastoma subgroups.

Shared by NobleBlocks on Feb 3, 2014 • 12:00 AM UTC

Authors:

Shih DJ

Northcott PA

Remke M

Abstract

<h4>Purpose</h4>Medulloblastoma comprises four distinct molecular subgroups: WNT, SHH, Group 3, and Group 4. Current medulloblastoma protocols stratify patients based on clinical features: patient age, metastatic stage, extent of resection, and histologic variant. Stark prognostic and genetic differ...

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