Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter.

T, Yoshikawa; H, Shimano; M, Amemiya-Kudo; N, Yahagi; AH, Hasty; T, Matsuzaka; H, Okazaki; Y, Tamura; Y, Iizuka; K, Ohashi; J, Osuga; K, Harada; T, Gotoda; S, Kimura; S, Ishibashi; N, Yamada

doi:10.1128/mcb.21.9.2991-3000.2001

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Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter.

Shared by NobleBlocks on May 1, 2001 • 12:00 AM UTC

Authors:

Yoshikawa T

Shimano H

Amemiya-Kudo M

Abstract

In an attempt to identify transcription factors which activate sterol-regulatory element-binding protein 1c (SREBP-1c) transcription, we screened an expression cDNA library from adipose tissue of SREBP-1 knockout mice using a reporter gene containing the 2.6-kb mouse SREBP-1 gene promoter. We cloned...

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