Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus.

CC, Wen; YH, Kuo; JT, Jan; PH, Liang; SY, Wang; HG, Liu; CK, Lee; ST, Chang; CJ, Kuo; SS, Lee; CC, Hou; PW, Hsiao; SC, Chien; LF, Shyur; NS, Yang

doi:10.1021/jm070295s

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Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus.

Shared by NobleBlocks on Jul 31, 2007 • 12:00 AM UTC

Authors:

Wen CC

Kuo YH

Jan JT

Abstract

In this study, 221 phytocompounds were evaluated for activity against anti-severe acute respiratory syndrome associated coronavirus (SARS-CoV) activities using a cell-based assay measuring SARS-CoV-induced cytopathogenic effect on Vero E6 cells. Ten diterpenoids (1-10), two sesquiterpenoids (11 and ...

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