Reprogramming of miRNA networks in cancer and leukemia.

S, Volinia; M, Galasso; S, Costinean; L, Tagliavini; G, Gamberoni; A, Drusco; J, Marchesini; N, Mascellani; ME, Sana; Jarour R, Abu; C, Desponts; M, Teitell; R, Baffa; R, Aqeilan; MV, Iorio; C, Taccioli; R, Garzon; Leva G, Di; M, Fabbri; M, Catozzi; M, Previati; S, Ambs; T, Palumbo; M, Garofalo; A, Veronese; A, Bottoni; P, Gasparini; CC, Harris; R, Visone; Y, Pekarsky; la Chapelle A, de; M, Bloomston; M, Dillhoff; LZ, Rassenti; TJ, Kipps; K, Huebner; F, Pichiorri; D, Lenze; S, Cairo; MA, Buendia; P, Pineau; A, Dejean; N, Zanesi; S, Rossi; GA, Calin; CG, Liu; J, Palatini; M, Negrini; A, Vecchione; A, Rosenberg; CM, Croce

doi:10.1101/gr.098046.109

Public

Reprogramming of miRNA networks in cancer and leukemia.

Shared by NobleBlocks on May 1, 2010 • 12:00 AM UTC

Authors:

Volinia S

Galasso M

Costinean S

Abstract

We studied miRNA profiles in 4419 human samples (3312 neoplastic, 1107 nonmalignant), corresponding to 50 normal tissues and 51 cancer types. The complexity of our database enabled us to perform a detailed analysis of microRNA (miRNA) activities. We inferred genetic networks from miRNA expression in...

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