Patterns of development of tachyphylaxis in patients with haemophilia and von Willebrand disease after repeated doses of desmopressin (DDAVP).

PM, Mannucci; D, Bettega; M, Cattaneo

doi:10.1111/j.1365-2141.1992.tb04598.x

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Patterns of development of tachyphylaxis in patients with haemophilia and von Willebrand disease after repeated doses of desmopressin (DDAVP).

Shared by NobleBlocks on Sep 1, 1992 • 12:00 AM UTC

Authors:

Mannucci PM

Bettega D

Cattaneo M

Abstract

When patients with mild haemophilia or von Willebrand disease (vWD) are repeatedly treated with desmopressin (DDAVP) at relatively short time intervals, some of them may become less responsive or unresponsive. The development of tachyphylaxis would limit the usefulness of DDAVP in clinical managemen...

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