The effects of particulate wear debris, cytokines, and growth factors on the functions of MG-63 osteoblasts.

C, Vermes; R, Chandrasekaran; JJ, Jacobs; JO, Galante; KA, Roebuck; TT, Glant

doi:10.2106/00004623-200102000-00007

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The effects of particulate wear debris, cytokines, and growth factors on the functions of MG-63 osteoblasts.

Shared by NobleBlocks on Feb 1, 2001 • 12:00 AM UTC

Authors:

Vermes C

Chandrasekaran R

Jacobs JJ

Abstract

<h4>Background</h4>Particle-challenged cells release cytokines, chemokines, and eicosanoids, which contribute to periprosthetic osteolysis. The particle-induced activation of macrophages and monocytes has been extensively studied, but only limited information is available on the response of osteobla...

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