HDAC6 expression is correlated with better survival in breast cancer.

Z, Zhang; H, Yamashita; T, Toyama; H, Sugiura; Y, Omoto; Y, Ando; K, Mita; M, Hamaguchi; S, Hayashi; H, Iwase

doi:10.1158/1078-0432.ccr-04-0455

Public

HDAC6 expression is correlated with better survival in breast cancer.

Shared by NobleBlocks on Oct 1, 2004 • 12:00 AM UTC

Authors:

Zhang Z

Yamashita H

Toyama T

Abstract

<h4>Purpose</h4>The structure and function of chromatin can be altered by modifications to histone. Histone acetylation in vivo is a dynamic reversible process governed by histone acetyltransferases (HATs) and histone deacetylases (HDACs). HDAC6 is a unique isoform among the HDACs, and a gene expres...

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