Genetic evidence for the involvement of τ in progressive supranuclear palsy

Conrad, C.; Andreadis, A.; Trojanowski, J.; Dickson, D.; Kang, D.; Chen, Xiaohua; Wiederholt, W.; Hansen, L.; Masliah, E.; Thal, L.; Katzman, R.; Xia, Yu; Saitoh, T.

doi:10.1002/ana.410410222

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Genetic evidence for the involvement of tau in progressive supranuclear palsy.

Shared by NobleBlocks on Feb 1, 1997 • 12:00 AM UTC

Authors:

C Conrad

A Andreadis

J Q Trojanowski

Abstract

A dinucleotide repeat polymorphism in a tau intron was identified and used in a case-control study to analyze the genetic association of tau with several neurodegenerative diseases with tau pathology. Subjects with the homozygous tau AO alleles were excessively represented in the progressive supranu...

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