mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H
                    <sup>+</sup>
                    -ATPase

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Shared by NobleBlocks on Nov 4, 2011 • 12:00 AM UTC

Authors:

Roberto Zoncu

Liron Bar-Peled

Alejo Efeyan

Abstract

Cellular sensing of amino acids occurs at the lysosome and is mediated by the vacuolar proton pump.

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