Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations.

SR, Lakhani; J, Jacquemier; JP, Sloane; BA, Gusterson; TJ, Anderson; de Vijver MJ, van; LM, Farid; D, Venter; A, Antoniou; A, Storfer-Isser; E, Smyth; CM, Steel; N, Haites; RJ, Scott; D, Goldgar; S, Neuhausen; PA, Daly; W, Ormiston; R, McManus; S, Scherneck; BA, Ponder; D, Ford; J, Peto; D, Stoppa-Lyonnet; YJ, Bignon; JP, Struewing; NK, Spurr; DT, Bishop; JG, Klijn; P, Devilee; CJ, Cornelisse; C, Lasset; G, Lenoir; RB, Barkardottir; V, Egilsson; U, Hamann; J, Chang-Claude; H, Sobol; B, Weber; MR, Stratton; DF, Easton

doi:10.1093/jnci/90.15.1138

Public

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations.

Shared by NobleBlocks on Aug 1, 1998 • 12:00 AM UTC

Authors:

Lakhani SR

Jacquemier J

Sloane JP

Abstract

<h4>Background</h4>We have previously demonstrated that breast cancers associated with inherited BRCA1 and BRCA2 gene mutations differ from each other in their histopathologic appearances and that each of these types differs from breast cancers in patients unselected for family history (i.e., sporad...

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