Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

Davies, G.; Armstrong, N.; Bis, J.; Bressler, J.; Chouraki, V.; Chouraki, V.; Giddaluru, S.; Hofer, E.; Ibrahim-Verbaas, C.; Kirin, M.; Lahti, J.; Lee, S.; Hellard, S.; Liu, Tian; Marioni, R.; Marioni, R.; Oldmeadow, C.; Postmus, I.; Smith, A.; A. Smith, Jennifer; Thalamuthu, A.; Thomson, R.; Vitart, V.; Wang, Jing; Wang, Jing; Yu, Lei; Zgaga, L.; Zgaga, L.; Zhao, Wei; Boxall, Ruth; Harris, S.; Hill, W.; Liewald, D.; Luciano, M.; Adams, H.; Ames, David; Ames, D.; Amin, N.; Amouyel, P.; A. Assareh, Amelia; Au, R.; Au, R.; Becker, J.; Beiser, Alexa; Beiser, Alexa; Berr, C.; Berr, C.; Bertram, L.; Bertram, L.; Boerwinkle, E.; Boerwinkle, E.; Buckley, B.; Campbell, H.; Corley, J.; Jager, P.; Jager, P.; Dufouil, C.; Dufouil, C.; Eriksson, J.; Eriksson, J.; Espeseth, T.; Faul, J.; Ford, Ian; Scotland, Generation; Gottesman, R.; E. Griswold, Michael; Gudnason, V.; Harris, T.; Heiss, G.; Hofman, A.; Holliday, E.; Huffman, J.; Kardia, S.; Kochan, N.; Knopman, D.; Kwok, J.; Kwok, J.; Lambert, J.; Lee, Teresa; Li, G.; Li, Shu-Chen; Li, Shu-Chen; Loitfelder, M.; Lopez, O.; Lundervold, A.; Lundervold, A.; Lundqvist, A.; Mather, K.; Mirza, S.; Nyberg, L.; Oostra, B.; Palotie, A.; Palotie, A.; Papenberg, G.; Papenberg, G.; Pattie, A.; Petrovic, K.; Polašek, O.; Psaty, B.; Psaty, B.; Redmond, P.; Reppermund, S.; Rotter, J.; Schmidt, H.; Schuur, M.; Schofield, P.; J. Scott, Rodney; Steen, V.; Stott, D.; Swieten, J.; Taylor, K.; Trollor, J.; Trompet, S.; Uitterlinden, A.; Weinstein, Galit; Weinstein, Galit; Widén, E.; Windham, B.; Jukema, J.; Wright, A.; Wright, M.; Yang, Qiong; Yang, Qiong; Amièva, H.; Attia, J.; Bennett, D.; Brodaty, H.; J. Craen, A.; Hayward, C.; Ikram, M.; Lindenberger, U.; Nilsson, L.; Porteous, D.; Räikkönen, K.; Reinvang, I.; Rudan, I.; Sachdev, P.; Schmidt, R.; Schofield, P.; Schofield, P.; Srikanth, V.; Srikanth, V.; Starr, J.; Turner, S.; Weir, D.; F. Wilson, James; Duijn, C.; Launer, L.; Fitzpatrick, A.; Seshadri, S.; Seshadri, S.; Mosley, T.; Deary, I.

doi:10.1038/mp.2014.188

Public

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

Shared by NobleBlocks on Feb 1, 2015 • 12:00 AM UTC

Authors:

G. Davies

N. Armstrong

J. Bis

Abstract

General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and well-being-related trait in middle-aged and older adults. We conducted a meta-analysis of genome-wide a...

Subject

Medicine

Psychology

Biology

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