Defective insulin signaling in placenta from pregnancies complicated by gestational diabetes mellitus.

M, Colomiere; M, Permezel; C, Riley; G, Desoye; M, Lappas

doi:10.1530/eje-09-0031

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Defective insulin signaling in placenta from pregnancies complicated by gestational diabetes mellitus.

Shared by NobleBlocks on Jan 29, 2009 • 12:00 AM UTC

Authors:

Colomiere M

Permezel M

Riley C

Abstract

<h4>Objective</h4>Studies in adipose tissue and skeletal muscle suggest that impaired insulin action is due to defects in the insulin signaling pathway and may play a role in the pathophysiology of insulin resistance associated with gestational diabetes mellitus (GDM) and obesity. The present study ...

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