A map of the interactome network of the metazoan C. elegans.

S, Li; CM, Armstrong; N, Bertin; H, Ge; S, Milstein; M, Boxem; PO, Vidalain; JD, Han; A, Chesneau; T, Hao; DS, Goldberg; N, Li; M, Martinez; JF, Rual; P, Lamesch; L, Xu; M, Tewari; SL, Wong; LV, Zhang; GF, Berriz; L, Jacotot; P, Vaglio; J, Reboul; T, Hirozane-Kishikawa; Q, Li; HW, Gabel; A, Elewa; B, Baumgartner; DJ, Rose; H, Yu; S, Bosak; R, Sequerra; A, Fraser; SE, Mango; WM, Saxton; S, Strome; Den Heuvel S, Van; F, Piano; J, Vandenhaute; C, Sardet; M, Gerstein; L, Doucette-Stamm; KC, Gunsalus; JW, Harper; ME, Cusick; FP, Roth; DE, Hill; M, Vidal

doi:10.1126/science.1091403

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A map of the interactome network of the metazoan C. elegans.

Shared by NobleBlocks on Jan 2, 2004 • 12:00 AM UTC

Authors:

Li S

Armstrong CM

Bertin N

Abstract

To initiate studies on how protein-protein interaction (or "interactome") networks relate to multicellular functions, we have mapped a large fraction of the Caenorhabditis elegans interactome network. Starting with a subset of metazoan-specific proteins, more than 4000 interactions were identified f...

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