Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.

SI, Hung; WH, Chung; ZS, Liu; CH, Chen; MS, Hsih; RC, Hui; CY, Chu; YT, Chen

doi:10.2217/pgs.09.162

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Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.

Shared by NobleBlocks on Mar 1, 2010 • 12:00 AM UTC

Authors:

Hung SI

Chung WH

Liu ZS

Abstract

<h4>Aims</h4>Compared with other categories of drugs, such as antibiotics and NSAIDs, antiepileptic therapies are associated with a high incidence of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). We previously reported that carbamazepine (CBZ)-SJS/TEN is strongly associated wi...

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