Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis.

SP, Fraser; JK, Diss; AM, Chioni; ME, Mycielska; H, Pan; RF, Yamaci; F, Pani; Z, Siwy; M, Krasowska; Z, Grzywna; WJ, Brackenbury; D, Theodorou; M, Koyutürk; H, Kaya; E, Battaloglu; Bella MT, De; MJ, Slade; R, Tolhurst; C, Palmieri; J, Jiang; DS, Latchman; RC, Coombes; MB, Djamgoz

doi:10.1158/1078-0432.ccr-05-0327

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Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis.

Published in Clinical cancer research : an official journal of the American Association for Cancer Research • Aug 1, 2005

Authors:

Fraser SP

Diss JK

Chioni AM

Abstract

<h4>Purpose</h4>Ion channel activity is involved in several basic cellular behaviors that are integral to metastasis (e.g., proliferation, motility, secretion, and invasion), although their contribution to cancer progression has largely been ignored. The purpose of this study was to investigate volt...

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