Bacteria‐Induced or Bacterial Product‐Induced Preterm Parturition in Mice and Rabbits Is Preceded by a Significant Fall in Serum Progesterone Concentrations

L. Fidel, Paul; Romero, Roberto; Maymon, Eli; Hertelendy, F.

doi:10.1002/(sici)1520-6661(199809/10)7:5<222::aid-mfm2>3.0.co;2-#

Public

Bacteria‐Induced or Bacterial Product‐Induced Preterm Parturition in Mice and Rabbits Is Preceded by a Significant Fall in Serum Progesterone Concentrations

Published in The Journal of Maternal-Fetal Medicine • Sep 1, 1998

Authors:

Paul L. Fidel

Roberto Romero

Eli Maymon

Abstract

Bacterial products are thought to induce labor by stimulating the production of pro-inflammatory cytokines and prostaglandins in gestational tissues, leading to the onset of preterm parturition. Progesterone withdrawal is a prerequisite of parturition in many species. Yet a role for progesterone in ...

View

Paywalled

Subject

Lipopolysaccharide

Gestation

Endocrinology

Generate AI Take for this paper

Highlights, strengths & weaknesses, commercial applications, and societal impact — written for this paper on demand.

Subject

Generate AI Take for this paper

Discussions