The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs.

T, Suzawa; C, Miyaura; M, Inada; T, Maruyama; Y, Sugimoto; F, Ushikubi; A, Ichikawa; S, Narumiya; T, Suda

doi:10.1210/endo.141.4.7405

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The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs.

Shared by NobleBlocks on Apr 1, 2000 • 12:00 AM UTC

Authors:

Suzawa T

Miyaura C

Inada M

Abstract

PGE2 functions as a potent stimulator of bone resorption. The action of PGE2 is thought to be mediated by some PGE receptor subtypes present in osteoblastic cells. In this study, we examined the involvement of PGE receptor subtypes, EP1, EP2, EP3, and EP4, in PGE2-induced bone resorption using speci...

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