Analysis of APC types involved in CD4 tolerance and regulatory T cell generation using reaggregated thymic organ cultures.

L, Guerri; I, Peguillet; Y, Geraldo; S, Nabti; V, Premel; O, Lantz

doi:10.4049/jimmunol.1202883

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Analysis of APC types involved in CD4 tolerance and regulatory T cell generation using reaggregated thymic organ cultures.

Shared by NobleBlocks on Jan 30, 2013 • 12:00 AM UTC

Authors:

Guerri L

Peguillet I

Geraldo Y

Abstract

Tolerance to self-Ags is generated in the thymus. Both epithelial and hematopoietic thymic stromal cells play an active and essential role in this process. However, the role of each of the various stromal cell types remains unresolved. To our knowledge, we describe the first comparative analysis of ...

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