A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies.

E McCue, Molly; L Bannasch, Danika; L Petersen, Jessica; Gurr, Jessica; Bailey, Ernie; M Binns, Matthew; Distl, Ottmar; Guérin, Gérard; Hasegawa, Telhisa; W Hill, Emmeline; Leeb, Tosso; Lindgren, Gabriella; Cecilia T Penedo, M; H Røed, Knut; A Ryder, Oliver; E Swinburne, June; Tozaki, Teruaki; J Valberg, Stephanie; Vaudin, Mark; Lindblad-Toh, Kerstin; M Wade, Claire; R Mickelson, James

doi:10.1371/journal.pgen.1002451

Public

A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies.

Shared by NobleBlocks on Jan 1, 2012 • 12:00 AM UTC

Authors:

Molly E McCue

Danika L Bannasch

Jessica L Petersen

Abstract

An equine SNP genotyping array was developed and evaluated on a panel of samples representing 14 domestic horse breeds and 18 evolutionarily related species. More than 54,000 polymorphic SNPs provided an average inter-SNP spacing of ∼43 kb. The mean minor allele frequency across domestic horse breed...

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