MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube.

Y, Saga; S, Miyagawa-Tomita; A, Takagi; S, Kitajima; Ji, Miyazaki; T, Inoue

doi:10.1242/dev.126.15.3437

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MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube.

Shared by NobleBlocks on Aug 1, 1999 • 12:00 AM UTC

Authors:

Saga Y

Miyagawa-Tomita S

Takagi A

Abstract

The Mesp1 gene encodes the basic HLH protein MesP1 which is expressed in the mesodermal cell lineage during early gastrulation. Disruption of the Mesp1 gene leads to aberrant heart morphogenesis, resulting in cardia bifida. In order to study the defects in Mesp1-expressing cells during gastrulation ...

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