Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease

Jernberg, Tomas; D. Payne, Christopher; J. Winters, Kenneth; Darstein, Christelle; T. Brandt, John; A. Jakubowski, Joseph; Naganuma, Hideo; Siegbahn, Agneta; Wallentin, Lars

doi:10.1093/eurheartj/ehi877

Public

Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease

Published in European Heart Journal • Apr 18, 2006

Authors:

Tomas Jernberg

Christopher D. Payne

Kenneth J. Winters

Abstract

AIMS: This study was designed to compare the degree of inhibition of platelet aggregation (IPA) of prasugrel with that of clopidogrel in stable aspirin-treated patients with coronary artery disease (CAD). METHODS AND RESULTS: Subjects (n=101) were randomly assigned to the following loading dose (LD)...

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Open Access

Subject

Prasugrel

Clopidogrel

Medicine

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