C-Type Lectins DC-SIGN and L-SIGN Mediate Cellular Entry by Ebola Virus in
 cis
 and in
 trans

P. Alvarez, Carmen; Lasala, Fátima; Carrillo, Jaime; Muñiz, Oscar; L. Corbí, Angel; Delgado, Rafael

doi:10.1128/jvi.76.13.6841-6844.2002

Public

C-Type Lectins DC-SIGN and L-SIGN Mediate Cellular Entry by Ebola Virus in cis and in trans

Shared by NobleBlocks on Jul 1, 2002 • 12:00 AM UTC

Authors:

Carmen P. Alvarez

Fátima Lasala

Jaime Carrillo

Abstract

ABSTRACT Ebola virus is a highly lethal pathogen responsible for several outbreaks of hemorrhagic fever. Here we show that the primate lentiviral binding C-type lectins DC-SIGN and L-SIGN act as cofactors for cellular entry by Ebola virus. Furthermore, DC-SIGN on the surface of dendritic cells is ab...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!