MHC class I chain related gene A (MICA) modulates the development of coeliac disease in patients with the high risk heterodimer DQA1*0501/DQB1*0201.

A, Lopez-Vazquez; L, Rodrigo; D, Fuentes; S, Riestra; C, Bousoño; S, Garcia-Fernandez; J, Martinez-Borra; S, Gonzalez; C, Lopez-Larrea

doi:10.1136/gut.50.3.336

Public

MHC class I chain related gene A (MICA) modulates the development of coeliac disease in patients with the high risk heterodimer DQA10501/DQB10201.

Shared by NobleBlocks on Mar 1, 2002 • 12:00 AM UTC

Authors:

Lopez-Vazquez A

Rodrigo L

Fuentes D

Abstract

<h4>Background and aims</h4>Coeliac disease (CD) is an enteropathic disorder characterised by a strong association with major histocompatibility complex (MHC) heterodimer HLA-DQ2. It has been suggested that other HLA class I genes in combination with DQ may also contribute to CD susceptibility. The ...

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