Microparticles harboring Sonic Hedgehog promote angiogenesis through the upregulation of adhesion proteins and proangiogenic factors.

R, Soleti; T, Benameur; C, Porro; MA, Panaro; R, Andriantsitohaina; MC, Martínez

doi:10.1093/carcin/bgp030

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Microparticles harboring Sonic Hedgehog promote angiogenesis through the upregulation of adhesion proteins and proangiogenic factors.

Shared by NobleBlocks on Jan 23, 2009 • 12:00 AM UTC

Authors:

Soleti R

Benameur T

Porro C

Abstract

Microparticles (MPs) are small fragments generated from the plasma membrane after cell stimulation or apoptosis. We have recently shown that MPs harboring the morphogen Sonic Hedgehog (MPs(Shh+)) correct endothelial injury by release of nitric oxide from endothelial cells [Agouni, Mostefai, Porro, C...

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