Serum N-Terminal Pro–Brain Natriuretic Peptide Is a Sensitive Marker of Myocardial Dysfunction in AL Amyloidosis

Palladini, Giovanni; Campana, Carlo; Klersy, Catherine; Balduini, Alessandra; Vadacca, Giovanbattista; Perfetti, Vittorio; Perlini, Stefano; Obici, Laura; Ascari, Edoardo; Melzi d’Eril, Gianvico; Moratti, Remigio; Merlini, Giampaolo

doi:10.1161/01.cir.0000068314.02595.b2

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Serum N-Terminal Pro–Brain Natriuretic Peptide Is a Sensitive Marker of Myocardial Dysfunction in AL Amyloidosis

Shared by NobleBlocks on May 20, 2003 • 12:00 AM UTC

Authors:

Giovanni Palladini

Carlo Campana

Catherine Klersy

Abstract

Background— Brain natriuretic peptide (BNP) is a marker of ventricular dysfunction and can be used to assess prognosis in heart failure and after myocardial infarction. Heart involvement is the most important prognostic factor and causes death in almost all patients with light-chain amyloidosis (AL)...

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