Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

Y, Chen; Y, Zheng; Y, Kang; W, Yang; Y, Niu; X, Guo; Z, Tu; C, Si; H, Wang; R, Xing; X, Pu; SH, Yang; S, Li; W, Ji; XJ, Li

doi:10.1093/hmg/ddv120

Public

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

Shared by NobleBlocks on Apr 9, 2015 • 12:00 AM UTC

Authors:

Chen Y

Zheng Y

Kang Y

Abstract

CRISPR/Cas9 has been used to genetically modify genomes in a variety of species, including non-human primates. Unfortunately, this new technology does cause mosaic mutations, and we do not yet know whether such mutations can functionally disrupt the targeted gene or cause the pathology seen in human...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!