Kupffer cells: increasingly significant role in nonalcoholic fatty liver disease.

Z, Wenfeng; W, Yakun; M, Di; G, Jianping; W, Chuanxin; H, Chun

doi:10.1016/s1665-2681(19)31247-5

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Kupffer cells: increasingly significant role in nonalcoholic fatty liver disease.

Shared by NobleBlocks on Sep 1, 2014 • 12:00 AM UTC

Authors:

Wenfeng Z

Yakun W

Di M

Abstract

Non-alcoholic fatty liver disease (NAFLD) is considered to be a manifestation of liver metabolic damage and is related to insulin resistance and genetic susceptibility. Inflammation mediated by Kupffer cells (KCs) is of critical importance to the development of NAFLD. The primary role of KCs in NAFL...

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