A randomized trial of adding insulin glargine vs. avoidance of insulin in people with Type 2 diabetes on either no oral glucose-lowering agents or submaximal doses of metformin and/or sulphonylureas. The Canadian INSIGHT (Implementing New Strategies with Insulin Glargine for Hyperglycaemia Treatment) Study.

HC, Gerstein; JF, Yale; SB, Harris; M, Issa; JA, Stewart; E, Dempsey

doi:10.1111/j.1464-5491.2006.01881.x

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A randomized trial of adding insulin glargine vs. avoidance of insulin in people with Type 2 diabetes on either no oral glucose-lowering agents or submaximal doses of metformin and/or sulphonylureas. The Canadian INSIGHT (Implementing New Strategies with Insulin Glargine for Hyperglycaemia Treatment) Study.

Shared by NobleBlocks on Jul 1, 2006 • 12:00 AM UTC

Authors:

Gerstein HC

Yale JF

Harris SB

Abstract

<h4>Aims</h4>Insulin is generally withheld until people with Type 2 diabetes are unresponsive to other therapies. However, its potential advantages suggest that it could be added earlier to achieve glycaemic goals; this possibility was tested in a clinical trial.<h4>Methods</h4>Consenting adults age...

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