The Hallucinogen
            <i>N,N</i>
            -Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator

Fontanilla, Dominique; Johannessen, Molly; R. Hajipour, Abdol; V. Cozzi, Nicholas; B. Jackson, Meyer; E. Ruoho, Arnold

doi:10.1126/science.1166127

Public

The Hallucinogen <i>N,N</i> -Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator

Shared by NobleBlocks on Feb 13, 2009 • 12:00 AM UTC

Authors:

Dominique Fontanilla

Molly Johannessen

Abdol R. Hajipour

Abstract

The sigma-1 receptor is widely distributed in the central nervous system and periphery. Originally mischaracterized as an opioid receptor, the sigma-1 receptor binds a vast number of synthetic compounds but does not bind opioid peptides; it is currently considered an orphan receptor. The sigma-1 rec...

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