Early alterations of the receptor-binding properties of H1, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals.

M, Matrosovich; A, Tuzikov; N, Bovin; A, Gambaryan; A, Klimov; MR, Castrucci; I, Donatelli; Y, Kawaoka

doi:10.1128/jvi.74.18.8502-8512.2000

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Early alterations of the receptor-binding properties of H1, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals.

Shared by NobleBlocks on Sep 1, 2000 • 12:00 AM UTC

Authors:

Matrosovich M

Tuzikov A

Bovin N

Abstract

Interspecies transmission of influenza A viruses circulating in wild aquatic birds occasionally results in influenza outbreaks in mammals, including humans. To identify early changes in the receptor binding properties of the avian virus hemagglutinin (HA) after interspecies transmission and to deter...

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