A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.

PS, Wild; T, Zeller; A, Schillert; S, Szymczak; CR, Sinning; A, Deiseroth; RB, Schnabel; E, Lubos; T, Keller; MS, Eleftheriadis; C, Bickel; HJ, Rupprecht; S, Wilde; H, Rossmann; P, Diemert; LA, Cupples; C, Perret; J, Erdmann; K, Stark; ME, Kleber; SE, Epstein; BF, Voight; K, Kuulasmaa; M, Li; AS, Schäfer; N, Klopp; PS, Braund; HB, Sager; S, Demissie; C, Proust; IR, König; HE, Wichmann; W, Reinhard; MM, Hoffmann; J, Virtamo; MS, Burnett; D, Siscovick; PG, Wiklund; L, Qu; Mokthari NE, El; JR, Thompson; A, Peters; AV, Smith; E, Yon; J, Baumert; C, Hengstenberg; W, März; P, Amouyel; J, Devaney; SM, Schwartz; O, Saarela; NN, Mehta; D, Rubin; K, Silander; AS, Hall; J, Ferrieres; TB, Harris; O, Melander; F, Kee; H, Hakonarson; J, Schrezenmeir; V, Gudnason; R, Elosua; D, Arveiler; A, Evans; DJ, Rader; T, Illig; S, Schreiber; JC, Bis; D, Altshuler; M, Kavousi; JC, Witteman; AG, Uitterlinden; A, Hofman; AR, Folsom; M, Barbalic; E, Boerwinkle; S, Kathiresan; MP, Reilly; CJ, O'Donnell; NJ, Samani; H, Schunkert; F, Cambien; KJ, Lackner; L, Tiret; V, Salomaa; T, Munzel; A, Ziegler; S, Blankenberg

doi:10.1161/circgenetics.110.958728

Public

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.

Shared by NobleBlocks on May 23, 2011 • 12:00 AM UTC

Authors:

Wild PS

Zeller T

Schillert A

Abstract

<h4>Background</h4>eQTL analyses are important to improve the understanding of genetic association results. We performed a genome-wide association and global gene expression study to identify functionally relevant variants affecting the risk of coronary artery disease (CAD).<h4>Methods and results</...

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