Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer.

MC, Cheang; SK, Chia; D, Voduc; D, Gao; S, Leung; J, Snider; M, Watson; S, Davies; PS, Bernard; JS, Parker; CM, Perou; MJ, Ellis; TO, Nielsen

doi:10.1093/jnci/djp082

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Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer.

Shared by NobleBlocks on May 12, 2009 • 12:00 AM UTC

Authors:

Cheang MC

Chia SK

Voduc D

Abstract

<h4>Background</h4>Gene expression profiling of breast cancer has identified two biologically distinct estrogen receptor (ER)-positive subtypes of breast cancer: luminal A and luminal B. Luminal B tumors have higher proliferation and poorer prognosis than luminal A tumors. In this study, we develope...

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