Phase II study of pemetrexed with and without folic acid and vitamin B12 as front-line therapy in malignant pleural mesothelioma.

GV, Scagliotti; DM, Shin; HL, Kindler; MJ, Vasconcelles; U, Keppler; C, Manegold; H, Burris; U, Gatzemeier; J, Blatter; JT, Symanowski; JJ, Rusthoven

doi:10.1200/jco.2003.06.122

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Phase II study of pemetrexed with and without folic acid and vitamin B12 as front-line therapy in malignant pleural mesothelioma.

Shared by NobleBlocks on Apr 1, 2003 • 12:00 AM UTC

Authors:

Scagliotti GV

Shin DM

Kindler HL

Abstract

<h4>Purpose</h4>This phase II clinical study evaluated the efficacy of pemetrexed for the treatment of malignant pleural mesothelioma (MPM).<h4>Patients and methods</h4>Patients with a histologically proven diagnosis of MPM, chemotherapy-naive measurable lesions, and adequate organ function received...

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